Biochemistry - Prolonged Preservation of the Heart Prior to Transplantation

Picture this. A reality is involved in a severe car crash in Florida which has left him brain-dead with no hope for any kind of recovery. The majority of his vital organs are still functional and the man has designated that his organs be donated to a aimy person upon his untimely death. Meanwhile, upon checking with the donor registry board, it is discovered that the best first mate for receiving the touchwood of the Florida man is a male in Oregon who is in desperate need of a essence transplant. Without the transplant, the man entrust most surely die within 48 hours. The second mans tissues equate up perfectly with the brain-dead mans in Florida. This seems like an pure opportunity for a heart transplant. However, a transplant is before long not a vi competent option for the Oregon man since he is separated by such a long geographic distance from the organ. Scientists and doctors are currently solely able to keep a donor heart workable for iv hours before the tissues become irreversibly damaged. Because of this preservation restriction, the donor heart is ultimately given to someone whose tissues do not match up as well, so there is a greatly increased chance for rejection of the organ by the recipient.

As removed as the man in Oregon goes, he will probably not receive a donor heart before his own expires. Currently, when a heart is being disposed(p) for transplantation, it is simply submerged in an isotonic saline icing bath in an attempt to stop all metabolic activity of that heart. This cold submersion technique is adequate for only four hours. However, if the heart is perfused with the proper media, it can remain viable for up to 24 hours. The technique of perfusion is based on per se simple principles. What occurs is a physician care ripey excises the heart from the donor. He then accurately trims... If you want to get a full essay, order it on our website: Ordercustompaper.com

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